A member asked:

Wat do + anti chromatin antibodies mean ? i have + ana, + chromatin = 5 (range 0-0.9). many sx's but can't get a dx from rheumatology. thanks !

2 doctors weighed in across 2 answers
Dr. Yelena Kipervas answered

Specializes in Family Medicine

Explanation : We do not have enough information for diagnosis. Lab results should be analyzed together with clinical presentation, what is absolutely absent in your question. Most likely your doctor need more tests for proper diagnosis, just wait and follow up with rheumatologist.

Answered 4/22/2017

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Caution with ANA: The ANA and chromatin antibodies are not to be used as screening tests due to the chance of false positives. If your "many symptoms" suggest the possibility of lupus erythematosus, then the full ANA panel needs to be done including chromatin, dsDNA, Sm, RNP, SSA, etc. However, the diagnosis of lupus is not made by labs tests but rather is made on history and physical examination. Good luck.

Answered 3/24/2018

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