A member asked:

If you have had steven johnson syndrome from an nsaid, can that person ever take a different kind of nsaid in the future?

12 doctors weighed in across 3 answers

Not always safe: Would be very careful Have your physician have you see an allergist

Answered 10/24/2017

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Dr. Hunter Handsfield answered

Specializes in Infectious Disease

NSAID allergy: Stevens Johnson syndrome can be very serious, sometimes even fatal. And your next reaction might be even more dangerous, e.g. anaphylaxis or angioedema. Most NSAIDs probably would not cross react with one another, but it may be possible. An allergy specialist might be able to provide better information, or even test you (e.g. skin tests) with various NSAIDs. Until then, best to avoid them all.

Answered 2/28/2017

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Dr. Luis Matos answered

Specializes in Pediatric Allergy and Asthma

At high risk: Stevens-Johnson reactions are not allergic so most of the data that talk about cross reactivity risk of anaphylaxis or risk of angioedema, all go out the window.. The immune reaction against the drug will trigger varying degrees of the Stevens-Johnson and no one really can test you for that. The only test is a challenge test and this could put you at risk of a life threatening reaction.

Answered 1/23/2017

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