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A 42-year-old member asked:

is zoloft (sertraline) bad for my liver?

3 doctor answers18 doctors weighed in
Dr. Horacio Capote
Specializes in Psychiatry
Probably Not: Although metabolized by the liver, zoloft (sertraline) is one of the milder antidepressants on the liver. If you are very concerned you can ask your doc to check your liver enzymes.
Dr. Leonard Lado
Psychiatry 32 years experience
Zoloft (sertraline) and liver: Zoloft (sertraline) is metabolized after going thru stomach anf liver by an enzyme cpy2b6. If this enzymes has an abnormal rate of metabolism which can be measure with a simple genetic test called assurerx it then gets excreted in the kidney half its amount in 26 hours. So the drug like any other does not necessarily cause liver disease but liver disease can affect how a drug is processed leading poor results.
Dr. Alan Ali
Dr. Alan Ali answered
Psychiatry 32 years experience
Zoloft (sertraline): As long as your liver profile testing is normal, no worries.

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Last updated Aug 27, 2018
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