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A 33-year-old member asked:

Can prolonged use of adderall (dextroamphetamine and racemic amphetamine) xr cause or contribute to adrenal failure?

2 doctor answers11 doctors weighed in
Dr. Adam Rosh
Emergency Medicine 18 years experience
Maybe: All medications have side effects, but to the best of my knowledge, long term use does not lead to adrenal insufficiency.
Dr. John O'Malley
Child Psychiatry 55 years experience
No Adrenal Failure: Adderall (dextroamphetamine and racemic amphetamine) or other stimulant medications do not cause adrenal failure (a serious life threatening disorder). In the popular magazines they talk about "adrenal fatigue" which ahas a variety of symptoms. There is little support in the science literature of this "syndrome". If you have symptoms that you have not had before, talk with your doctor and see if a workup is necessary.
Last updated Nov 28, 2017

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