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A 45-year-old female asked:

Is 200mg of benadryl too much to take with klonopin 1mg and 4mg tizanidine i accidentally took more benadryl than usual?

2 doctor answers7 doctors weighed in
Dr. Stephen Kibrick
Clinical Psychology 46 years experience
Yes,Not recommended: These drugs all interact, and the effects are additive. Your usual doses of Klonopin and Tizanidine are well within normal limits. The maxiumum dose of Benadryl is 300mg/day. You may experience dizziness, drowsiness, and impaired coordination with higher dose of Benadryl added to these. Half life of Benadryl is 9 hrs or less, so after a day it is mostly out of your system. Be careful w/ dose!
Dr. Lynne Weixel
Clinical Psychology 36 years experience
Dizzy?: Each of these can cause drowsy or dizzy feelings and more so in combo - Also, the usual benadryl dose is 25-50mg so that is a lot you took - but the danger dose is 300mg/day so you're probably not at risk if you don't do anything foolish like drive. Be careful and try to reduce need for drugs if possible - discuss your needs w/ Dr to help.

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Last updated Sep 20, 2016

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