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A 33-year-old male asked:

what is the definition or description of: depakote overdose?

1 doctor answer2 doctors weighed in
Dr. Edward Workman
Specializes in Pain Management
OD=toxic blood level: Manifestations of depakote OD are: Hyperthermia/hypothermia, Tachycardia, Hypotension (with severe overdose), Cardiac arrest (with severe overdose), Respiratory depression necessitating intubation. Typical dosing of depakote are 500mg 2-3 times per day for seizures and bipolar disorder. However, the blood level is what really matters. The therapeutic l range= 50-125ug/ml; toxic range=>150ug/ml.

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A 45-year-old member asked:

How can a previous drug overdose affect my pregnancy?

2 doctor answers5 doctors weighed in
Dr. Raj Syal
Dr. Raj Syalanswered
Obstetrics and Gynecology 33 years experience
Unlikely: A previous drug overdose is unlikely to affect this pregnancy.
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A 39-year-old member asked:

If my allergies are really bad, do I need to worry about overdosing on allergy meds?

2 doctor answers5 doctors weighed in
Dr. Patrick Melder
ENT and Head and Neck Surgery 27 years experience
No: If taken as prescribed, you should not have issues at all. Most allergy meds are anti-histamines ... An over-dosage is just going to cause disruptions in alertness, dry mouth, etc. But if your allergy meds aren't working... See out an ENT who does allergy or an allergist. You may be a candidate for immunotherapy - you may get to the point you could stop taking meds all together.
A 40-year-old member asked:

Can you really die from an overdose of diphenhydramine?

2 doctor answers6 doctors weighed in
Dr. Steven Machtinger
Allergy and Immunology 44 years experience
Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic.
A 34-year-old member asked:

What will happen if I have a Flonase overdose?

2 doctor answers3 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
Depends: How big an overdose? If its just a few extra sprays a few times, likely nothing will happen. If it is many sprays a day over months or years, you run the low risk of systemic absorption and typical steroid side effects. This can include secondary infection, weight gain, cataracts, liver changes, osteoporosis etc. This would be rare and require a massive overdose.
A 46-year-old member asked:

Does xenical safe with depakote?

1 doctor answer2 doctors weighed in
Dr. Adam Nally
Family Medicine 40 years experience
Yes: Depakote should not be taken with food, as food decreases the absorption of the depakote. Xenical should be taken with a meal. There is a strong possibility that xenical will decrease the absorption of Depakote if taken together. Both medications are metabolized in the liver, therefore, close monitoring of liver function is essential.

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Last updated Jun 10, 2017
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