OD=toxic blood level: Manifestations of depakote OD are: Hyperthermia/hypothermia, Tachycardia, Hypotension (with severe overdose), Cardiac arrest (with severe overdose), Respiratory depression necessitating intubation. Typical dosing of depakote are 500mg 2-3 times per day for seizures and bipolar disorder. However, the blood level is what really matters. The therapeutic l range= 50-125ug/ml; toxic range=>150ug/ml.
Answered 6/10/2017
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