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A 40-year-old male asked:
How long after coming off aciphex (rabeprazole) until your system is normal. ?
3 doctor answers • 3 doctors weighed in
Dr. Julie Abbottanswered
Preventive Medicine 47 years experience
A couple days: Aciphex/rabeprazole is a proton pump inhibitor: these drugs bind to an enzyme (proton pump) located on stomach parietal cells and block the production of hydrogen ions. So then the hydrogen ions can't combine with chloride ions to form gastric/stomach acid. This blockage/inhibition lasts about 48 hours after which new proton pumps are synthesized and resting proton pumps are reactivated. Stay well
Created for people with ongoing healthcare needs but benefits everyone.
1k viewsReviewed >2 years ago
Dr. Marissa Chesneyanswered
General Practice 14 years experience
24-48 hours: The medication has a half life of 1-2 hours, so it is no longer in your system somewhere between 3 and 12 hours after your last dose, depending on your individual metabolism of the medication.
Created for people with ongoing healthcare needs but benefits everyone.
1k viewsAnswered >2 years ago
Dr. Michael Safdianswered
Gastroenterology 48 years experience
Depends: What dose and how long did you take the Aciphex (rabeprazole)?
Most people start making acid within 48 hrs. It may be slightly more than usual initially but should revert to normal within a week.
Generally there are no other effects on your system.
Created for people with ongoing healthcare needs but benefits everyone.
1k viewsAnswered >2 years ago
Last updated Sep 17, 2016
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