A patient with 5-year history of parkinson's disease, takes no drug treatment.is there any advanced treatment protocol to this condition in the us?

Confused: Please repost your question with an explanation of WHY this patient is on no medications; and also what you mean by "advanced treatment protocol." How is that different in your mind from the usual sort of treatment that one would get from a community neurologist?

Sort of: We have some newer forms of L-DOPA, like Duodopa, and Rytary, and Deep Brain Stimulation seems to be used earlier and in more patients, but otherwise, not any profound advances, so far. However, loads of research programs under supervision of some outstanding Movement Disorder Specialists. If you are available, there may be some areas of benefit to consider.