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A 28-year-old member asked:

Is taking 100mg of nortriptalyne with 150mg of bupropion x-r long term safe? is this a healthy liver combo for someone who used to drink very heavily?

1 doctor answer • 2 doctors weighed in

Dr. Charles Cattanoanswered

Gastroenterology 41 years experience

Risky combination: Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of nortriptyline, which may increase other side effects. Ref: https://www.drugs.com/interactions-check.php?drug_list=440-0,1734-0

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Dr. Heidi Fowler

Dr. Heidi Fowler agrees1 doctor agrees

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