U.S. doctors online nowAsk doctors free
Hilo, HI
A 28-year-old member asked:

Is taking 100mg of nortriptalyne with 150mg of bupropion x-r long term safe? is this a healthy liver combo for someone who used to drink very heavily?

1 doctor answer2 doctors weighed in
Dr. Charles Cattano
Gastroenterology 41 years experience
Risky combination: Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of nortriptyline, which may increase other side effects. Ref: https://www.drugs.com/interactions-check.php?drug_list=440-0,1734-0
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 17, 2017


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.