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A 28-year-old female asked:

Ct showed splenomegaly. blood work had high rdw, low creatinine, and low mch (anemia?); other cbc normal. how could anemia be related to spleen?

1 doctor answer1 doctor weighed in
Dr. Lewis Hassell
Pathology 41 years experience
Splenomegaly: It isn't clear from what you say whether your hemoglobin itself is truly abnormal or whether just the RDW and MCH are altered. These in themselves do not define anemia. A large spleen may be related to trapping altered red cells, or actually making more blood (extramedullary hemopoiesis.) Often a high RDW means that there is increased production of immature red cells after destruction in spleen
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Last updated Jun 9, 2016


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