Prednisone: or any cortisone derivative medication has upper gastrointestinal effects and heartburn, upper GI pain are common. Omeprazole is NOT and ACUTE treatment thus unless you take it regularly it may not help! An H-2 Blocker (eg: PEPCID (famotidine) AC) may offer sopme protective value as will TAKING THE PERDNISONE WITH MILK!!!! Hope this helpsd! Dr Z
Answered 5/7/2016
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