Hello doctor, i am on a hormone replacement therapy for menopause. could this cause some pain in breasts?

Yes: Occasional mild breast tenderness on post-menopausal hormone therapy is not uncommon.It may however indicate that your dosing is too high. There is variation in the metabolism of estrogen in different women. Alcohol consumption may slow the clearance of estrogen. Breast pain in general needs evaluation. You should schedule an appointment with the doctor that prescribed your estrogen