Why do i have extreme fatigue after some bowel movements & usually after eating? *i was told i have acid reflux and just started nexium (esomeprazole) in am b4 food.

Fatigue: There is a very long list of conditions and situations that lead to fatigue, so many other factors must be considered. A full evaluation includes analysis of daily habits and lifestyle (are you getting enough sleep?) plus a full medical history and exam to look for systemic causes. It's unlikely but not impossible that the Nexium (esomeprazole) is contributing, if the fatigue started after beginning that med.