A member asked:

Just took 25 mg of benadryl (diphenhydramine) will that counter-act/ make my prozac and klonopin that i took earlier not effective?

2 doctors weighed in across 2 answers
Dr. Al Hegab answered

Specializes in Allergy and Immunology

No, but: rather benadryl (diphenhydramine) and klonopin combo would cause CNS suppression and psychomotor impairment, so watch out , don't drive or operate machinery, and try not to combine them again, good that you asked, always exercise caution with multiple medications, wish you wellness

Answered 1/20/2016

1.7k views

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Dr. Charles Turck answered

Specializes in Pharmacology

No it won’t: Taking benadryl (diphenhydramine) in addition to prozac and klonopin will not counteract the effects. Just be careful with taking it too close to the klonopin because they both cause drowsiness.

Answered 1/20/2016

1.7k views

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