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Johnson City, TN
A 58-year-old female asked:

is nucynta (tapentadol) safe to take with harvoni . i have an f 2, a1/2 fibrosis liver score? i have 2 herniated discs and can't take asa,tylenol, or nsaid.

1 doctor answer1 doctor weighed in
Dr. Edward Hellman
Orthopedic Surgery 29 years experience
Yes and no: On one hand, nucynta is a narcotic that does not have Tylenol (acetaminophen) or NSAID in it, so that is good in your case. On the other hand, it is metabolized by the liver. And so if you do have issues with your liver it would be best to discuss with your doctor about whether it would be sdvisable in your specific case.

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