About a week: Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. Cotinine levels <10 ng/ml -non smoker 10 ng/ml to 100 ng/ml are associated with light smoking or moderate passive exposure and levels above 300 ng/ml are seen in heavy smokers.
Answered 8/13/2018
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