Can you take a 1mg ativan (lorazepam) on 90 mg of methadone ?

Extremely risky: Combining the Ativan (lorazepam) and Methadone can potentially cause additive effects of sedation and respiratory depression. Both are considered central nervous system depressants. In severe cases it can cause death. Amounts that would cause toxicity vary between individuals due to differences in tolerability, age, and general medical condition. Recommend discussion with your doctor.

Not recommended: Methadone levels in your body might increase when mixed with Ativan (lorazepam). Always talk to your doctor about the pros and cons of your individual situation.