Yes: Generally yes. However, benzonatate can cause drowsiness. The first generation antihistamines (such as benadryl, (diphenhydramine) doxepin, chlorpheniramine, and hydroxyzine), can also cause drowsiness. Hence, the affect could be additive. With that in mind, you might want to consider taking a second generation antihistamine such as cetirizine, xyzal, fexofenadine, etc.
Answered 10/18/2018
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