A member asked:

How do you know when aricept and namenda (memantine) have stopped working?

A doctor has provided 1 answer

Tough to be sure: These medicines are designed to help slow the progression of Alzheimer's disease. Since it doesn't necessarily improve symptoms, it can be difficult to know if it is working or not. There have been some studies with Aricept (donepezil) showing that even in severely demented individuals, there is still benefit. If there is no quality of life (i.e. No communication, no adls), i would stop the medicine.

Answered 2/15/2019

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