A member asked:

Does it make pharmacological sense to take 20mg fluoxetine 1 wk per month or better to take it daily for pmdd?

7 doctors weighed in across 2 answers

Daily: Fluoxetine is not effective if taken intermittently. It may take several weeks of daily dosing to reach a therapeutic blood level. Be sure to clarify directions with prescribing doctor. I hope this helps.

Answered 4/30/2016

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Dr. David Lipkin answered

Specializes in Internal Medicine

Take it for 2 weeks: Several studies have shown that taking fluoxetine for 14 days, starting on cycle day 14, is effective for PMDD. This is called luteal phase-only treatment. see>http://1.usa.gov/1fKRIro

Answered 8/28/2015

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Is Paxil (paroxetine) or Prozac good for pmdd?

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