It can: Breast enlargement and tenderness are common with estrogen supplements. Common adverse effects are vaginal spotting, mood changes, headache or abdominal pain, weight gain (not all from breast enlargement). It increases risk of blood clots. When combined with progesterone, estrogen is a safe and common method of birth control. For breast enlargement in a healthy female, risk > potential benefit
Answered 6/15/2016
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