Interaction between lorazepam and amitrityline?

Additive sedation: Both are sedating medications and when taken together, sedation is compounded. However, a doctor can prescribe medication with additive and compounded effect as long as this is factored into the dosage, timing and the clinical condition of the patient as well as use of alcohol.

Check & see: You can use a drug interaction checker whenever you have questions about drug-drug interactions or drug - food interactions. Here is one option (Drugs.Com): https://www.drugs.com/drug_interactions.php Your pharmacist is also an excellent source of information.