Within few minutes : An intramuscular shot of penicillin statrs to work within few minutes as soon as it is absorped in blood stream and keeps working till another shot is given for short acting procaine penicillin, but long acting penicillin is given as one shot for certain treatmemts and do not need repeat shots.
Answered 3/19/2016
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Depends: It depends on the type of infection that is being treated and on the type of penicillin in the shot.
Answered 1/5/2019
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