A member asked:

Can i take one oxycodone and my regular 200 mg of zoloft (sertraline) for one ttime?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

Not recommended: oxycodone increases effects of Zoloft (sertraline) by added drug effects. Always talk to your prescribing physician before combining medications.

Answered 5/1/2016

2.7k views

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