A member asked:

Will clarithromycin have any adverse reactions with lsd? i've read that it inhibits cyp3a4 but i can't find out if that is involved in lsd metabolism.

2 doctors weighed in across 2 answers
Dr. Sean Agazanof answered

Specializes in Pharmacology

Wait: I would suggest waiting as you mentioned in your Yahoo post. There is overlap in the metabolic pathways of your liver. Dont work it too hard because it may take longer for either drug to clear. This is important because at higher doses Clarithromycin is likely to have side effects such as QT prolongation. LSD acts on brain in humans to incr heart rate. QT prolong + tachycardia= risk of DEATH.

Answered 5/23/2015

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Dr. Alan Ali answered

Specializes in Psychiatry

LSD & P450: LSD is metabolized by unspecified Cytochrome P450 enzymes, hence there would be an effect with most other P450 inhibitors.

Answered 5/23/2015

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Will lsd abuse kill me if I don't get treatment?

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