Yes: Read the label and know the potential adverse effects of Benadryl (diphenhydramine) before using. Recommend starting with 50mg dose and can repeat 3-4hrs later if needed. Hives in association with new diarrhea are almost certainly a result of the immune response to infection and should clear up shortly. If they return after Benadryl (diphenhydramine), consider longer acting, newer-generation antihistamine such as cetirizine.
Answered 5/8/2015
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