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A member asked:

Went cold turkey zoloft 200mg to lexapro (escitalopram) 20mg. feeling lethargic and unmotivated. how long until these feelings pass?

3 doctors weighed in across 2 answers

3-4 weeks: These medicines take at least 3,weeks to start therapeutic effect.

Dr Raff agreed

Answered 5/8/2015

2.9k views

Thank

Cross tapering meds: If the lethargy and lack of motivation are from your underlying depression you need to give it a minimum of 3 weeks to begin to improve. If they are side effects of medication withdrawal they will wear off soon

Answered 12/2/2020

22 views

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