A member asked:

How long does depo provera (medroxyprogesterone) wears off the body?

2 doctors weighed in across 2 answers
Dr. Cynthia Frazier answered

Specializes in Gynecology

12 months: The contraceptive effect of Depo-Provera lasts 12-13 weeks but after stopping injections it may be as long as 12 months before menses resume.

Answered 5/5/2015

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Dr. Natalie Sieb answered

Specializes in Family Medicine

Months: It takes about 3 months to get out of your system, which is why you have to be very diligent about getting your next shot right around the exact time 3 months after your last one to ensure you have proper birth control protection. And remember to still use condoms because it does not protect you from STDs. Best wishes!

Answered 5/5/2015

2.9k views

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