A member asked:

Can benadryl (diphenhydramine) make your prostate enlarge?

5 doctors weighed in across 2 answers
Dr. John Feola answered

Specializes in Internal Medicine

SIDE EFFECT: NO: BENADRYL (diphenhydramine) AND ANTIHISTAMINES IN GENERAL CAN CAUE URINARY RETENTION. This is more likely I n men with BPH.

Answered 4/29/2015

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No but: No but it can certainly impair urination through it's anticholinergic effect.

Answered 11/27/2015

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