I took 3 prescription 5/325 vicodin/day on th and fri. last dose 5:30pm fri. had a vodka cocktail sat 6:30pm. is acetaminophen poisoning a concern?

No: While there are some people with very sensitive livers, this reported amount of acetaminophen intake really shouldn't create any significant issues.

The toxic level of tylenol is over 4,000 mg daily, and you are far below that. You do not reveal why you are taking a narcotic analgesic, or whether it is finished at this point. If that is the case, your alcohol consumption will not be a problem.