A member asked:

Just started taking 150ml of wellbutrin (bupropion) 5 days ago(along with 25mg zoloft), have been feeling weird the last 2 nights(anxiety, heavy head). bad???

A doctor has provided 1 answer

Initial reaction: It appears that you are experiencing an initial reaction to the norepinephrine and dopamine action, which is the basic pharmacologic effect of Wellbutrin (bupropion). It is advisable to start with the immediate release Bupropion, at 37.5 mg daily for about a week, increase to 75 mg and then the Wellbutrin (bupropion) XL 150 mg daily. If you also started the Zoloft recently, that could also cause some initial side effects

Answered 4/20/2015

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Thank

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