What can cause pulling sensation in legs from around knee down to above ankle esp. when lying down and driving. husband says i often twitch when sleep

Restless Legs: U get sensations in lower legs between the knees & ankles. There is discomfort unless u move your legs, mostly at night when lay down or in daytime when sit down , like creepy crawlers feelings, may last for @ an hour, & u feel the urge to move or walk. Symptoms worsen during stress & relieved by moving about. Can interfere with sleep.

Likely restless leg: Your symptoms suggesting possible restless leg syndrome. It is quite common and mostly occurs during sleep. Symptoms can vary quite a bit from mild tingling/itching, crawling, burning, aching to severe pain etc.. and a need to move It seems a bit more common in females. Thyroid diseases, iron deficiency, pregnancy are just few examples of common causes. I recommend checking with doc. Good luck