A member asked:

Cauc, 30 & 1st preg. negative triple and nt test on 1st screen. 1/6123 risk for ds. 20 week screen showed fetal nasal bone at 4.6mm. high risk for ds?

3 doctors weighed in across 2 answers
Dr. Brian Nguyen answered

Specializes in Obstetrics and Gynecology

Fairly unlikely: Fetal nasal bone length is not a commonly assessed marker at 20wks gestation, instead we care more at 11-13wks. As fetuses grow, epigenetics and the environment have more of an effect on growth so a small nasal bone at this gestational age is not necessarily predictive in the setting of other reassuring testing. A noninvasive blood test may help to provide more reassurance.

Answered 1/5/2019

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Dr. Cynthia Archer answered

Specializes in Internal Medicine

DS still unlikely: Your risk basecd on the earlier markers is more meaningful than the nasal bone at 20 weeks. What did your obstetrician say? Having a look at the baby's gender and what your family bone structure looks like might help put you at ease. The risk of losing the pregnancy due to CVS or Amniocentesis is higher than the risk of Trisomy 21. Try and relax, chances are highest your baby will be "normal".

Answered 4/6/2015

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