A member asked:

Will 250mcg or advair diskus (salmeterol and fluticasone) effect a methacholine test?

A doctor has provided 1 answer
Dr. John Chiu answered

Yes: Both the steroid and long acting bronchodilator would likely produce a false-negative test. The minimum one must stay off of Advair would be 2 weeks. On the other hand, if one were to check how the medication works, one can compare the response before and after starting Advair- mostly done in research setting.

Answered 4/2/2015

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