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A member asked:
What pain relievers can be taken with zoloft (sertraline) for a headache?
4 doctors weighed in across 2 answers
Most: There is no drug interaction with NSAIDs or opiates. However if a tricyclic antidepressant is used for pain control , it may affect the effect of Zoloft (sertraline). However there may be an additive sedating effect from opiates.
Answered 3/28/2015
3k views
Mostly safe except: Concomitant SSRI (e.g. Zoloft) use with NSAID's & aspirin can increase bleeding in high risk individuals. NSAID's may also diminish the therapeutic effect of SSRI's. Use with tramadol, some other opiate, triptans, & tricyclics may increase risk for serotonin syndrome. QT-interval prolongation is another concern. It can increase concentration of hydrocodone. Acetaminophen is the safest OTC choice.
Answered 3/27/2015
3k views
Related Questions
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My husband has been taking risperidone and Zoloft (sertraline) and has a headache, can he take over-the-counter meds for it?
A doctor has provided 1 answer
A member asked:
My husband is on risperidone and Zoloft (sertraline) and is experiencing awful headaches, is there anything he can take over-the-counter for it?
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A member asked:
How much time does nausea and headaches take to go away after stopping zoloft (sertraline)?
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