A member asked:

Tbi pt titrating down with prednisone. steady increase in depression with decrease in prednisone dose. now at 13mg. suggestions? adrenal fatigue?

14 doctors weighed in across 3 answers
Dr. Lynne Weixel answered

Specializes in Clinical Psychology

Referrals: W/o prior adrenal disease, only lengthy, high dose prednisone could result in them underperforming and leading to depression. It's more likely reactive depression and a Psych Eval may help. So may followup by neurologist from TBI. A course of therapy w/ Health Psychologist may help adjust to injury/aftermath.

Answered 10/9/2017

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Unavoidable: Prednisone and steroids make people anxious, manic or psychotic, withdrawal leads to depression. This usually resolves with time (2 weeks) but antidepressant might help. TBI patients are like CVA pts with risk of mood disorder tx with antidepressants and mood stabilizers

Answered 11/27/2017

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Dr. Corey Clay answered

Specializes in Allergy and Immunology

Taper: How long on pred? Couple of weeks? Is the desired effect for TBI complete and now just tapering down? Seems like you may be ok with a faster taper (by 5mg every 2-3 days) as long as it is no longer needed for swelling.

Answered 11/27/2017

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