Not one chemical: There is tremendous debate on the causative agent of alcohol. Most people think that it is a combination of factors, including the production of acetaldehyde (a metabolite of alcohol), congeners in different drinks (more hangovers with red than white wine, more with whiskey than with vodka/gin, and probably hereditary or acquired personal differences - severe in some, mild or absent in others.
Answered 3/24/2015
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