Yes: Side effect of depo-provera, like most drugs, can occur at different times. You can experience a side effect of depo-provera that you have not experienced previously, at any time. Also, you may have side effects that come and go. The symptoms you describe could be side effects of depo-provera, or may be a sign of something else. If you have had unprotected sex, you should be tested for STDs.
Answered 3/3/2015
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