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A member asked:
Is sickle cell crisis more severe in sickle cell thalassemia or sickle cell alone?
A doctor has provided 1 answer
Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B(0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B(+)thal: has 60% HbSS and 30% HbA, thus less severe than HbSS (sickle cell alone). HbS/A-thal: less severe than HbSS due to decreased HbSS amount.
Answered 2/27/2015
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