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A 35-year-old male asked:

Is tapentadol considered stronger than tramadol ?

2 doctor answers3 doctors weighed in
Dr. Andrew Shiller
Physical Medicine and Rehabilitation 26 years experience
Yes, usually: tapentadol is a strong opioid (narcotic) and a has a compound that reduces the breakdown of norepinephrine, Tapentadol only binds the mu opioid receptors Tramadol has less intense opioid action than tapentadol, but it binds a broader spectrum of opioid receptors. It inhibits breakdwon of serotonin. Tapentadol is 'stronger', for most people. Some people might not respond as well to it.
Dr. David Rosenfeld
Pain Management 27 years experience
Yes: Nucynta is much stronger than tramadol

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