Absolutely NOT!: The combination of alcohol and Methotrexate has caused many people to have liver failure requiring a liver transplant to survive.Methotrexate can irritate the liver by itself but is quite safe at the low weekly doses used to treat many autoimmune conditions.Never drink any alcohol while on methotrexate.If you absolutely "must" drink alcohol, tell your doc so he/she can take you off methotrexate.
Answered 4/29/2017
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2 doctors weighed in across 2 answers
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