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A 37-year-old member asked:

i'm on methotrexate, can i still drink?

1 doctor answer2 doctors weighed in
Dr. Robert Lowe
Pediatric Rheumatology 17 years experience
Absolutely NOT!: The combination of alcohol and Methotrexate has caused many people to have liver failure requiring a liver transplant to survive.Methotrexate can irritate the liver by itself but is quite safe at the low weekly doses used to treat many autoimmune conditions.Never drink any alcohol while on methotrexate.If you absolutely "must" drink alcohol, tell your doc so he/she can take you off methotrexate.

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A 35-year-old member asked:

Do you have information on methotrexate uses and effects?

2 doctor answers3 doctors weighed in
Dr. Thomas Namey
Rheumatology 48 years experience
Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra!
A 31-year-old member asked:

Any methotrexate side effects?

1 doctor answer3 doctors weighed in
Dr. Thomas Namey
Rheumatology 48 years experience
Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid.
A 48-year-old member asked:

What is important to know about methotrexate for ra?

1 doctor answer1 doctor weighed in
Dr. Thomas Namey
Rheumatology 48 years experience
Everything!: Consensus drug of first choice by the acr and eular (american & european rheumatology groups for treating moderate to severe ra. Frequently given with other drugs such as plaquenyl, sulfasalazine, or low dose prednisone. I beleve it is better to take subcutaneously, rather than oral. Should be given with folic acid.
A 48-year-old member asked:

Does methotrexate work for patients with ra?

1 doctor answer3 doctors weighed in
Dr. Thomas Namey
Rheumatology 48 years experience
Very well.: Consensus drug of first choice by the acr and eular (american & european rheumatology groups for treating moderate to severe ra. Frequently given with other drugs such as plaquenyl, sulfasalazine, or low dose prednisone.
A 36-year-old member asked:

What are the comon side effects for methotrexate when used for ectopic?

1 doctor answer2 doctors weighed in
Dr. PAUL EUN
Dr. PAUL EUN answered
Obstetrics and Gynecology 38 years experience
Not many: When Methotrexate is used to treat ectopic pregnancy, usually only one dose needs to be given. Therefore, most women will do well without any side effects. If they do have side effects, it will be mild and temporary. They include nausea, abdominal pain, sores in the mouth, dizziness, etc.

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Last updated Apr 29, 2017
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