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A member asked:
When morphine administrated with diazepam they both will increase the sedative effect .. is there a specific mechanism of action for that ?
9 doctors weighed in across 2 answers
Mechanisms: Morphine and diazepam are both CNS depressants. Depending on dosage, could be lethal.
Answered 5/4/2017
5.2k views
Sedative effects: When administering a narcotic, such as morphine , which has sedative effects along with analgesic or pain relief effects in addition to a benzodiazepam, such as diazepam, which has sedative effects together these can cause increased sedative effects an also respiratory depression which can be a dangerous combination. The mechanism is mediated via central nervous system depression.
Answered 11/27/2017
5.2k views
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