A Biopsy is Required: The only way to tell the difference between the different types of lymphoma is to have a biopsy and have a pathologist examine the cells under the microscope and perform different stains to identify features of the cells. Traditionally surgical removal of the entire node (or at least a large part of it) was needed, but today a diagnosis can at times be made with a needle biopsy.
Answered 1/26/2015
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