Possible: Depo-provera is usually a pretty reliable method of birth control; however, no birth control option is 100% effective (except abstinence), so there is a possibility your girlfriend can get pregnant on any birth control method. Depo-provera shots have to be given every 3 months; if your girlfriend is late in getting her next shot, the effectiveness of the Depo-Provera is decreased.
Answered 11/18/2019
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