Can a person who takes imitrex (sumatriptan) for migraines build a tolerance to the drug? having to eventually increase dose or change medications?

Is it the right med?: I have seen many, many people who do not respond to typical migraine medications (imitrex, relpax, (eletriptan) maxalt, etc) because they don't have true migraines. Often time any bad headache is diagnosed as a migraine. There are many other types of headaches that can be just as bad (tension, cluster, rebound, etc) that do not respond to those treatments. Confirm that your diagnosis is correct first!

Maybe: But a more accurate explanation is that you may be treating the wrong condition with the wrong med. Since many people have mixed headache patterns, and since most bad headaches come out of the neck, these pain patterns will not respond to triptans. Many people have secondary migraines where the triptan will help, but if more of your pain is from other comditions, then you will need different tx.