Will changing manufacturers change the effectiveness of alprazolam? the pharmacy made a change and i feel a little more anxious. still the same dosage

Maybe: Different generic medication manufacturers do not necessarily keep to exactly the same standard for their medications. They adhere to the fdas "20% rule" which states that a generic medication needs to be within 20% of the efficacy of the name brand medication in order to call it bioequivalent. Thus, your new meds could have slightly lower efficacy, though it is also possible to be reversed.

It can happen: Yes, this can happen -- and is why some psychiatrists prefer to use brand names rather than generics. Of course, this comes into conflict with insurance companies who have formularies -- and often pay only for generics. Like patients, most psychiatrists would prefer to have more predictable results than be wondering what generic the drug store purchased that month.