I have a 14 year old brother that has severe acne and we tried almost ever thing can u help?

See a dermatologist: There are multiple options for treating acne including oral and topical antibiotics, topical retinoids (e.g.: Retin-A and others) and an oral retinoid (synthetic vitamin a analogue) called Isotretinoin (commonly known as accutane). This latter medication in highly effective in adolescent males but does have some potential side effects and is prescribed almost exclusively by dermatologists.