A member asked:

Is edwards syndrome dominant or recessive , can it be inherited?

5 doctors weighed in across 4 answers

Neither : Edward syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. It cannot be inherited as all cases are fatal before reproductive age. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 nbr 18th chm to the other parents nbr 18, 3 end up in the egg & the excess 18 causes the all the problems.

Answered 2/29/2016

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Dr. Oscar Novick answered

Specializes in Pediatrics

Neither: It is neither dominant or recessive. Rather it is caused by duplication of chromosome 18. It is not inherited.

Answered 2/29/2016

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Neither: It is a trisomy like the more common down syndrome.It can be inherited if a parent was a genetic abnormality. It could be a spontaneous aberration. Genetic testing of both parents should be considered.

Answered 11/28/2017

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Edwards Syndrome: Trisomy 18 - chromosomal condition in 1/5,000 to 6,000 live births due to random events while egg or sperm form.Usually not inherited. 5 to 10% live past 12 months. May have small jaw, mouth & head, low-set ears, short sternum, heart defects, low birth wt, clenched fists, contracted joints, seizures, scoliosis, spina bifida, high BP, cleft palate & lip, hearing loss & mental retardation.

Answered 7/28/2020

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