A member asked:

I am prediabetic and taking 500 mg of metformin. i have lost 10 lbs and have about 30 lbs to go. is all safe with metformin/safe with my prediabetes?

5 doctors weighed in across 3 answers
Dr. James Cunnar answered

Specializes in Family Medicine

For sure: Keep it up! if you hit your weight goal, you may be able to get off the metformin. The combination of metformin and Alli should help significantly with your weight loss. But be careful - the combination may cause some unwanted side effects, particularly foul smelling and/or greasy stools.

Answered 3/10/2019

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No: Alli can be taken safely by prediabetics. But it should not be taken together with metformin as it can increase the risk of a serious, potentially life-threatening condition called lactic acidosis!

Answered 6/24/2014

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Dr. Slade Suchecki answered

Specializes in Family Medicine

I wouldn't: The drug you mention is designed to block fat. It will erupt, as my fellow physician reports. Mostly, this is a behavioral modification. If you eat fat, it will go straight through you. Just avoid the fat and save your money.

Answered 7/20/2012

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