A member asked:

How long does it take for tylenol (acetaminophen) to wear off?

A doctor has provided 1 answer

4 - 6 hours average: The half life is about 4 - 6 hours and that is the recommended interval between doses as it begins to wear off during that interval. Body size, presence of food and metabolism can change this some.

Answered 6/25/2018

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